radC
168
probable DNA repair protein
Locus
BSU_28040
Molecular weight
26.00 kDa
Isoelectric point
7.83
Function
DNA repair
Product
probable DNA repair protein
Essential
no
Synonyms
radC, ysxA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2003 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,861,840 2,862,535
The protein
Protein family
UPF0758 family (single member, according to UniProt)
MPN domain (aa 109-231) (according to UniProt)
Structure
2QLC (PDB) (C-terminal domain of Chlorobium tepidum RadC, 46% identity)
Modification
phosphorylated on Arg-59 PubMed
cytoplasm (Homogeneous) PubMed
Expression and Regulation
Operons
Description
Regulation
constitutively expressed PubMed
Regulatory mechanism
Sigma factors
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Biological materials
Mutant
GP3561 (ΔradC::aphA3), available in Jörg Stülke's lab
MGNA-B011 (ysxA::erm), available at the NBRP B. subtilis, Japan
References
MreB-Dependent Inhibition of Cell Elongation during the Escape from Competence in Bacillus subtilis.
PLoS genetics. 2015 Jun; 11(6):e1005299. doi:10.1371/journal.pgen.1005299. PMID:26091431
Complete Genome Sequence of Bacillus subtilis Phage {varphi}105.
Genome announcements. 2013 Sep 05; 1(5). doi:10.1128/genomeA.00641-13. pii:e00641-13. PMID:24009114
Global impact of protein arginine phosphorylation on the physiology of Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America. 2012 May 08; 109(19):7451-6. doi:10.1073/pnas.1117483109. PMID:22517742
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science (New York, N.Y.). 2012 Mar 02; 335(6072):1103-6. doi:10.1126/science.1206848. PMID:22383849
Bacillus subtilis σ(V) confers lysozyme resistance by activation of two cell wall modification pathways, peptidoglycan O-acetylation and D-alanylation of teichoic acids.
Journal of bacteriology. 2011 Nov; 193(22):6223-32. doi:10.1128/JB.06023-11. PMID:21926231
The Bacillus subtilis sigma(M) regulon and its contribution to cell envelope stress responses.
Molecular microbiology. 2008 Feb; 67(4):830-48. doi:10.1111/j.1365-2958.2007.06090.x. PMID:18179421
SigM-responsive genes of Bacillus subtilis and their promoters.
Journal of bacteriology. 2007 Jun; 189(12):4534-8. . PMID:17434969
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics. 2006 Apr; 6(7):2135-46. . PMID:16479537
SigM, an extracytoplasmic function sigma factor of Bacillus subtilis, is activated in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress.
Journal of bacteriology. 2003 Jun; 185(12):3491-8. . PMID:12775685
Whole-genome analysis of genes regulated by the Bacillus subtilis competence transcription factor ComK.
Journal of bacteriology. 2002 May; 184(9):2344-51. . PMID:11948146
Microarray analysis of the Bacillus subtilis K-state: genome-wide expression changes dependent on ComK.
Molecular microbiology. 2002 Mar; 43(5):1331-45. . PMID:11918817
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Time of last update: 2025-07-29 12:14:47
Author of last update: MBenda