sknR

168

transcriptional repressor (Xre family) of the yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqaN operon of the skin element

Locus: BSU_26350

Molecular weight: 13.17 kDa

Isoelectric point: 5.42

Protein length: 116 aa

Gene length: 351 bp

Function: control of prophage gene expression

Product: transcriptional repressor (Xre family)

Essential: yes

Synonyms: sknR, yqaE

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG1396 (Galperin et al., 2021)

Gene

Coordinates: 2,698,893  2,699,243

Phenotypes of a mutant

• essential in the wild type background (due to overexpression of the toxic proteins YqaH and YqaM) PubMed
• no phenotype if deleted with the complete skin element PubMed

The protein

Catalyzed reaction/ biological activity

• binds the yqaF promoter region to repress transcription of the ''yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqzO-yqaN'' operon PubMed

Protein family

• Xre family

Domains

• HTH cro/C1-type domain (aa 6-60) (according to UniProt)

Structure

• P45902 (AlphaFold)

Paralogous protein(s)

• YonR, Xre

Expression and Regulation

Operons

• Genes: sknR

  Description: PubMed

References

Loading