ylxM

168

putative signal recognition particle (SRP) component

Locus: BSU_15970

Molecular weight: 13.02 kDa

Isoelectric point: 4.54

Protein length: 110 aa

Gene length: 333 bp

Function: presecretory protein translocation

Product: putative signal recognition particle (SRP) component

Essential: no

Synonyms: ylxM

Genomic Context

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List of homologs in different organisms, belongs to COG2739 (Galperin et al., 2021)

Gene

Coordinates: 1,671,828  1,672,160

The protein

Protein family

• UPF0122 family (single member, according to UniProt)

Structure

• 1XSV (PDB) (from Staphylococcus aureus, 54% identity)
• P37104 (AlphaFold)

Expression and Regulation

Operons

• Genes: ylxM-ffh-rpsP-khpA

  Description: PubMed

  Regulation

  • the mRNA is processed between ffh and rpsP by RNase Y, this requires the RicA-RicF-RicT complex PubMed

  Expression

  • expression is decreased upon depletion of tRNA maturation factors rnpB or rnz PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in sigA regulon

• Genes: ylxM-ffh-rpsP-khpA-ylqD-rimM-trmD-rplS

  Description: PubMed

  Regulation

  • the mRNA is processed between ffh and rpsP by RNase Y, this requires the RicA-RicF-RicT complex PubMed

  Expression

  • expression is decreased upon depletion of tRNA maturation factors rnpB or rnz PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in sigA regulon

Biological materials

Mutant

• BKE15970 (ylxM::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTGAGCTCTCCCCTTTG,  downstream forward: _UP4_AAATTAGATTAGGAGGCGGC
• BKK15970 (ylxM::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTGAGCTCTCCCCTTTG,  downstream forward: _UP4_AAATTAGATTAGGAGGCGGC

References

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