bpsB

168

methyltransferase, involved in polyketide synthesis

locus: BSU_22040

Molecular weight: 19.17 kDa

pI: 9.55

Protein length: 168 aa

Gene length: 507 bp

function: polyketide synthesis

product: methyltransferase

essential: no

ec: null

synonyms: bpsB, ypbQ

List of homologs in different organisms, belongs to COG1755 (Galperin et al., 2021)

Gene

Coordinates: 2,316,446  2,316,952

The protein

Catalyzed reaction/ biological activity

• conversion of triketide pyrones to alkylpyrone methyl ethers [Pubmed|19465653]

Structure

• [AF|P54158]

Expression and Regulation

Operons

• genes: [gene|7D90F7AF49BAD6A95731BF805991DEBBBCAFA46C|bpsA]-[gene|6BAF5763249305F27326F941A34956396B3F8C99|bpsB]

  description: [Pubmed|19465653]

Biological materials

Mutant

• MGNA-A876 (ypbQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/876 NBRP B. subtilis, Japan]
• BKE22040 ([gene|6BAF5763249305F27326F941A34956396B3F8C99|bpsB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22040 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GGCGATCAACAACCAAAACA,  downstream forward: _UP4_TAGCGATTGAAAATCATTCT
• BKK22040 ([gene|6BAF5763249305F27326F941A34956396B3F8C99|bpsB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22040 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_GGCGATCAACAACCAAAACA,  downstream forward: _UP4_TAGCGATTGAAAATCATTCT

References

• 19465653,20525796