lutB
168
lactate catabolic enzyme
Locus
BSU_34040
Molecular weight
53.31 kDa
Isoelectric point
5.85
Function
lactate utilization
Product
lactate oxidase
Essential
no
Synonyms
lutB, yvfW
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1139 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,493,519 3,494,958
Phenotypes of a mutant
no growth with lactate as the single carbon source PubMed
The protein
Catalyzed reaction/ biological activity
oxidation of lactate to pyruvate PubMed
Protein family
LutB/YkgF family (single member, according to UniProt)
2 4Fe-4S ferredoxin-type domains (aa 304-334, aa 353-382) (according to UniProt)
[4Fe-4S] cluster
Structure
Modification
phosphorylated on Arg-33 PubMed
Expression and Regulation
Operons
Description
Regulation
induction by lactate PubMed
Regulatory mechanism
LutR: repression, in lutR regulon
Sigma factors
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Other regulations
Biological materials
Mutant
MGNA-A498 (yvfW::erm), available at the NBRP B. subtilis, Japan
Labs working on this gene/protein
Richard Losick, Harvard Univ., Cambridge, USA homepage
References
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Time of last update: 2025-02-24 10:49:54
Author of last update: Jstuelk