nadC
168
nicotinate-nucleotide diphosphorylase (carboxylating)
Locus
BSU_27860
Molecular weight
31.24 kDa
Isoelectric point
5.18
Function
NAD biosynthesis
Product
nicotinate-nucleotide diphosphorylase (carboxylating)
Essential
no
E.C.
2.4.2.19
Synonyms
nadC, yrxB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0157 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,847,048 2,847,917
The protein
Catalyzed reaction/ biological activity
CO2 + diphosphate + nicotinate β-D-ribonucleotide --> 5-phospho-α-D-ribose 1-diphosphate + 2 H+ + quinolinate (according to UniProt)
Protein family
nadC/modD family (single member, according to UniProt)
Structure
1X1O (PDB) (from Thermus thermophilus, 45% identity)
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Biological materials
Mutant
References
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Time of last update: 2025-05-01 00:22:53
Author of last update: Melvin.boenninger