bstG

168

bacillithiol S-transferase, nuclease inhibitor

Locus: BSU_05630

Molecular weight: 19.76 kDa

Isoelectric point: 5.61

Protein length: 172 aa

Gene length: 519 bp

Function: response to DNA damage

Product: bacillithiol S-transferase, nuclease inhibitor

Essential: no

Synonyms: bstG, dinB

Genomic Context

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Categories containing this gene/protein

Information processing, Genetics, DNA repair/ recombination

Information processing, Genetics, DNA repair/ recombination, Other proteins

List of homologs in different organisms, belongs to COG2318 (Galperin et al., 2021)

Gene

Coordinates: 608,246 → 608,764

Phenotypes of a mutant

reduced formation of rpsB or rpsE suppressor mutants after mitomycin treatment PubMed

The protein

Protein family

S-transferase-like (STL) superfamily PubMed
DinB family (according to UniProt)

Structure

Q02886 (AlphaFold)

Expression and Regulation

Operons

Genes: bstG

Description: PubMed

Regulation

induced by DNA damage (LexA) PubMed

Regulatory mechanism

LexA: repression, PubMed, in lexA regulon

Additional information

the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

Mutant

BKE05630 (ΔbstG::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTTAAAATTCCCCCTTT,  downstream forward: _UP4_TAAAAAAGCGGCTCCCTAAA
BKK05630 (ΔbstG::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTTAAAATTCCCCCTTT,  downstream forward: _UP4_TAAAAAAGCGGCTCCCTAAA

References

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