yvrE

168

glucono-lactonase, general stress protein, similar to senescence marker protein-30

Locus: BSU_33200

Molecular weight: 33.05 kDa

Isoelectric point: 4.62

Protein length: 292 aa

Gene length: 879 bp

Function: survival of salt stress

Product: glucono-lactonase

Essential: no

Synonyms: yvrE

Genomic Context

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List of homologs in different organisms, belongs to COG3386 (Galperin et al., 2021)

Gene

Coordinates: 3,405,664  3,406,542

The protein

Catalyzed reaction/ biological activity

• glucoco-lactonase PubMed

Protein family

• SMP-30/CGR1 family (single member, according to UniProt)

Structure

• 3G4E (PDB) (the human protein, 33% identity) PubMed
• O34940 (AlphaFold)

Expression and Regulation

Operons

• Genes: yvrE

  Description: PubMed

  Regulation

  • induced by stress (SigB) PubMed

  Sigma factors

  • SigB: sigma factor, PubMed, in sigB regulon

• Genes: yvrHb-yvrG-yvrE

  Description: PubMed

Additional information

• translation is substantially enhanced when the gene is transcribed by SigB-RNA polymerase PubMed

Biological materials

Mutant

• MGNA-B048 (yvrE::erm), available at the NBRP B. subtilis, Japan
• BKE33200 (yvrE::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTGTTACACCTCTTTAG,  downstream forward: _UP4_TAAAAAAAACGCATCCGAAA
• BKK33200 (yvrE::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTGTTACACCTCTTTAG,  downstream forward: _UP4_TAAAAAAAACGCATCCGAAA

References

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