yabN

168

similar to nucleoside triphosphate pyrophosphohydrolase

Locus: BSU_00580

Molecular weight: 55.94 kDa

Isoelectric point: 4.51

Protein length: 489 aa

Gene length: 1470 bp

Function: unknown

Product: unknown

Essential: no

Synonyms: yabN

Genomic Context

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Categories containing this gene/protein

Groups of genes, Proteins of unknown function

List of homologs in different organisms, belongs to COG3956 (Galperin et al., 2021)

This gene is a member of the following regulons

SigE regulon, SigM regulon, SigW regulon, SigD regulon, SigX regulon

Gene

Coordinates: 66,405  67,874

The protein

Domains

contains a domain similar to  E. coli mazG (nucleoside pyrophosphohydrolase) at the C-terminus (aa 240-480)

Structure

3CRA (PDB) (E. coli MazG, corresponds to the C-terminal domain, aa 238 ... 486), 43.6% identity PubMed
P37556 (AlphaFold)

Expression and Regulation

Operons

Genes: yabM-yabN-rqcP-yabP-shfA-divIC-yabR

Description: PubMed

Regulation

expressed during sporulation (SigE) PubMed

Sigma factors

SigM: sigma factor, PubMed, in sigM regulon
SigE: sigma factor, PubMed, in sigE regulon
SigW: sigma factor, PubMed, in sigW regulon
SigD: sigma factor, PubMed, in sigD regulon
SigX: sigma factor, PubMed, in sigX regulon

Biological materials

Mutant

MGNA-B915 (yabN::erm), available at the NBRP B. subtilis, Japan
BKE00580 (yabN::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GGCACCAAGTCCGACGACTG,  downstream forward: _UP4_GAAACTGAGAGGAGATCATA
BKK00580 (yabN::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GGCACCAAGTCCGACGACTG,  downstream forward: _UP4_GAAACTGAGAGGAGATCATA

References

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