lytA

168

secretion of major autolysin LytC

Locus: BSU_35640

Molecular weight: 11.09 kDa

Isoelectric point: 4.06

Protein length: 102 aa

Gene length: 309 bp

Function: autolysis

Product: secretion of major autolysin LytC

Essential: no

Synonyms: lytA, lppX

Genomic Context

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Categories containing this gene/protein

Cellular processes, Cell envelope and cell division, Cell wall degradation/ turnover, Autolysis

Groups of genes, Membrane proteins

List of homologs in different organisms

This gene is a member of the following regulons

SigA regulon, SigD regulon, SinR regulon, YvrHb regulon, SlrR regulon

Gene

Coordinates: 3,662,789  3,663,097

The protein

Structure

Q02112 (AlphaFold)

Localization

cell membrane (according to UniProt)

Expression and Regulation

Operons

Genes: lytA-lytB-lytC

Description: PubMed

Expression

expression is heterogeneous PubMed

Regulatory mechanism

SinR: repression, in sinR regulon
YvrHb: repression, PubMed, in yvrHb regulon
SlrR: repression, (in complex with SinR) PubMed, in slrR regulon

Sigma factors

SigA: sigma factor, PubMed, in sigA regulon
SigD: sigma factor, PubMed, in sigD regulon

Biological materials

Mutant

1A789 ( lytA::kan), PubMed, available at BGSC
BKE35640 (lytA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTTTTCACCTCATTAT,  downstream forward: _UP4_TAAGATATAGGGAGGAACCT
BKK35640 (lytA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTTTTCACCTCATTAT,  downstream forward: _UP4_TAAGATATAGGGAGGAACCT

References

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