tuaC

168

sugar transferase

Locus: BSU_35590

Molecular weight: 43.12 kDa

Isoelectric point: 9.75

Protein length: 389 aa

Gene length: 1170 bp

Function: biosynthesis of teichuronic acid

Product: sugar transferase

Essential: no

Synonyms: tuaC, yvhC

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0438 (Galperin et al., 2021)

Gene

Coordinates: 3,655,586  3,656,755

The protein

Protein family

• glycosyltransferase 1 family (according to UniProt)
• Glycosyltransferase 4 subfamily (according to UniProt)

Structure

• 3C48 (PDB) (from Corynebacterium glutamicum, 27% identity) PubMed
• O32272 (AlphaFold)

Expression and Regulation

Operons

• Genes: tuaA/2-tuaA/1-tuaB-tuaC-tuaD-tuaE-tuaF-tuaG-tuaH

  Description: PubMed

  Regulation

  • expressed during sporulation in the forespore (SigF) PubMed

  Regulatory mechanism

  • PhoP: activation, PubMed, in phoP regulon

  Sigma factors

  • SigA: sigma factor, PubMed, in sigA regulon
  • SigF: sigma factor, PubMed, in sigF regulon

Biological materials

Mutant

• BKE35590 (tuaC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CTTCATGACAAACGTCCTTT,  downstream forward: _UP4_TAATCGTAAGACACTGCGAC
• BKK35590 (tuaC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CTTCATGACAAACGTCCTTT,  downstream forward: _UP4_TAATCGTAAGACACTGCGAC

References

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