Rho

• Description: transcriptional termination protein
  
  

Gene name	rho
Synonyms
Essential	no
Product	transcriptional termination protein
Function	transcriptional termination
Gene expression levels in SubtiExpress: rho
Interactions involving this protein in SubtInteract: Rho
MW, pI	48 kDa, 6.865
Gene length, protein length	1281 bp, 427 aa
Immediate neighbours	rpmE, glpX
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription

The gene

Basic information

• Locus tag: BSU37080

Database entries

• BsubCyc: BSU37080

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: rho family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • Rho-NusG (C-terminal domain) (based on data for E. coli) PubMed

• Localization:

Database entries

• BsubCyc: BSU37080

• Structure: 1PVO (Rho from E. coli) PubMed

• UniProt: Q03222

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: rho PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 154 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 477 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

François D'Heygère, Makhlouf Rabhi, Marc Boudvillain
Phyletic distribution and conservation of the bacterial transcription termination factor Rho.
Microbiology (Reading): 2013, 159(Pt 7);1423-1436
[PubMed:23704790] [WorldCat.org] [DOI] (I p)

Marc Boudvillain, Nara Figueroa-Bossi, Lionello Bossi
Terminator still moving forward: expanding roles for Rho factor.
Curr Opin Microbiol: 2013, 16(2);118-24
[PubMed:23347833] [WorldCat.org] [DOI] (I p)

M Sofia Ciampi
Rho-dependent terminators and transcription termination.
Microbiology (Reading): 2006, 152(Pt 9);2515-2528
[PubMed:16946247] [WorldCat.org] [DOI] (P p)

John P Richardson
Loading Rho to terminate transcription.
Cell: 2003, 114(2);157-9
[PubMed:12887917] [WorldCat.org] [DOI] (P p)

J P Richardson
Structural organization of transcription termination factor Rho.
J Biol Chem: 1996, 271(3);1251-4
[PubMed:8576105] [WorldCat.org] [DOI] (P p)