rplT

168

ribosomal protein bL20

Locus: BSU_28850

Molecular weight: 13.50 kDa

Isoelectric point: 11.9

Protein length: 119 aa

Gene length: 360 bp

Function: translation

Product: ribosomal protein L20 (bL20)

Essential: yes

Synonyms: rplT

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0292 (Galperin et al., 2021)

Gene

Coordinates: 2,952,224  2,952,583

Phenotypes of a mutant

• essential PubMed

The protein

Catalyzed reaction/ biological activity

• excess RplT binds the untranslated region of the infC-rpmI-rplT-ysdA operon mRNA to terminate transcription PubMed

Protein family

• bacterial ribosomal protein bL20 family (single member, according to UniProt)

Structure

• 3J9W (PDB) (the ribosome) PubMed
• P55873 (AlphaFold)

Localization

• cytosolic large ribosomal subunit (according to UniProt)

Expression and Regulation

Operons

• Genes: infC-rpmI-rplT-ysdA

  Description: PubMed

  Regulation

  • Rel dependent downregulation (Class I) during stringent response PubMed

  Regulatory mechanism

  • stringent response: negative regulation, in stringent response
  • RplT: termination, via binding to a RNA switch in the infC leader region causes transcription termination, in rplT regulon

  Additional information

  • autorepression of infC-rpmI-rplT-ysdA expression upon binding of excess RplT to the untranslated region of the mRNA PubMed
  • expression of IF3 is uncoupled from that of L35 and L20 by RNase Y-dependent mRNA processing PubMed
  • the RNA switch RNA is degraded by RNase Y PubMed

References

Loading