Difference between revisions of "YloH"

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* '''Additional information:'''  
 
* '''Additional information:'''  
 
** present about at half the amount of core [[RNA polymerase]] {{PubMed|20724389}}
 
** present about at half the amount of core [[RNA polymerase]] {{PubMed|20724389}}
 +
** number of protein molecules per cell (minimal medium with glucose and ammonium): 486 {{PubMed|24696501}}
 +
** number of protein molecules per cell (complex medium with amino acids, without glucose): 758 {{PubMed|24696501}}
  
 
=Biological materials =
 
=Biological materials =

Revision as of 09:31, 17 April 2014

Gene name yloH
Synonyms
Essential no
Product omega subunit of RNA polymerase
Function unknown
Gene expression levels in SubtiExpress: yloH
Interactions involving this protein in SubtInteract: YloH
Metabolic function and regulation of this protein in SubtiPathways:
yloH
MW, pI 7 kDa, 5.513
Gene length, protein length 201 bp, 67 aa
Immediate neighbours gmk, yloI
Sequences Protein DNA DNA_with_flanks
Genetic context
YloH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YloH expression.png















Categories containing this gene/protein

transcription

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15690

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) (according to Swiss-Prot)
  • Protein family: RNA polymerase subunit omega family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • present about at half the amount of core RNA polymerase PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 486 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 758 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Lakshminarayan M Iyer, L Aravind
Insights from the architecture of the bacterial transcription apparatus.
J Struct Biol: 2012, 179(3);299-319
[PubMed:22210308] [WorldCat.org] [DOI] (I p)

Original publications

Additional publications: PubMed

L Minakhin, S Bhagat, A Brunning, E A Campbell, S A Darst, R H Ebright, K Severinov
Bacterial RNA polymerase subunit omega and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly.
Proc Natl Acad Sci U S A: 2001, 98(3);892-7
[PubMed:11158566] [WorldCat.org] [DOI] (P p)