yerC

168

similar to HisR repressor of S. aureus

Locus: BSU_06580

Molecular weight: 11.89 kDa

Isoelectric point: 4.85

Protein length: 104 aa

Gene length: 315 bp

Function: unknown

Product: unknown

Essential: no

Synonyms: yerC

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG4496 (Galperin et al., 2021)

Gene

Coordinates: 716,431 → 716,745

Phenotypes of a mutant

• inactivation of yerC reduces sporulation efficiency to 10% that of wild type cells PubMed

The protein

Structure

• 3KOR (PDB) (Trp repressor of Staphylococcus aureus, 67% identity)
• Q7BVT7 (AlphaFold)

Expression and Regulation

Operons

• Genes: yerB-yerC

  Description: PubMed

  Regulation

  • expressed under conditions that trigger sporulation (Spo0A) PubMed

  Regulatory mechanism

  • Spo0A: activation, PubMed, in spo0A regulon

• Genes: yerA-yerB-yerC

  Description: PubMed

Biological materials

Mutant

• MGNA-A924 (yerC::erm), available at the NBRP B. subtilis, Japan
• BKE06580 (ΔyerC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GCGTAATTTATCGATTTGCA,  downstream forward: _UP4_TAAAAAACCGCCCTGCCGTC
• BKK06580 (ΔyerC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GCGTAATTTATCGATTTGCA,  downstream forward: _UP4_TAAAAAACCGCCCTGCCGTC

References

Loading