yknW

168

modulates assembly of the YknX-YknY-YknZ ABC transporter for the export of the SdpC toxin

Locus: BSU_14340

Molecular weight: 24.03 kDa

Isoelectric point: 6.94

Protein length: 231 aa

Gene length: 696 bp

Function: resistence against SdpC toxin

Product: modulator of ABC transporter assembly

Essential: no

E.C.: null

Synonyms: yknW

Genomic Context

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List of homologs in different organisms

Gene

Coordinates: 1,503,582  1,504,277

The protein

Structure

• O31709 (AlphaFold)

Localization

• cell membrane (according to UniProt),  membrane PubMed

Expression and Regulation

Operons

• Genes: yknU-yknV-yknW-yknX-yknY-yknZ

  Description: PubMed

• Genes: yknW-yknX-yknY-yknZ

  Description: PubMed

  Regulation

  • repressed during logrithmic growth (AbrB) PubMed

  Regulatory mechanism

  • AbrB: repression, PubMed, in abrB regulon

  Sigma factors

  • SigW: sigma factor, PubMed, in sigW regulon

Biological materials

Mutant

• MGNA-B348 (yknW::erm), available at the NBRP B. subtilis, Japan
• BKE14340 (yknW::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTCAAAACCTCCTTGAG,  downstream forward: _UP4_AATTCTGTGGCGGGTGCATA
• BKK14340 (yknW::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTCAAAACCTCCTTGAG,  downstream forward: _UP4_AATTCTGTGGCGGGTGCATA

References

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