YxxG

• Description: immunity protein, protects the cell against the toxic activity of WapA
  
  

Gene name	yxxG
Synonyms	wapI
Essential	no
Product	immunity protein
Function	intercellular competition
Gene expression levels in SubtiExpress: yxxG
Interactions involving this protein in SubtInteract: YxxG
MW, pI	16 kDa, 4.424
Gene length, protein length	426 bp, 142 aa
Immediate neighbours	yxiF, wapA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, phosphoproteins,

This gene is a member of the following regulons

DegU regulon, WalR regulon, YvrHb regulon

The gene

Basic information

• Locus tag: BSU39220

Phenotypes of a mutant

• severe growth defect PubMed

Database entries

• BsubCyc: BSU39220

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • YxxG inhibits the toxic activity of WapA PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylation on (Tyr-102 OR Ser-105) PubMed

• Cofactors:

• Effectors of protein activity:

• Interactions:
  • WapA-YxxG PubMed

• Localization:

Database entries

• BsubCyc: BSU39220

• Structure:

• UniProt: Q07836

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: wapA-yxxG PubMed

• Expression browser: yxxG PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed at high salt concentration (DegU-P) PubMed

• Regulatory mechanism:
  • DegU-P: transcription repression PubMed
  • activated by YvrHb PubMed
  • WalR: transcription repression PubMed

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 2912 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 1271 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: