natA

168

Na⁺ ABC transporter (export) (ATP-binding protein)

Locus: BSU_02750

Molecular weight: 27.73 kDa

Isoelectric point: 8.8

Protein length: 246 aa

Gene length: 741 bp

Function: sodium export

Product: Na⁺ ABC transporter (export) (ATP-binding protein)

Essential: no

Synonyms: natA

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG4555 (Galperin et al., 2021)

Gene

Coordinates: 296,429 → 297,169

The protein

Catalyzed reaction/ biological activity

• ATP + H₂O + Na⁺ --> ADP + H⁺ + Na⁺ + phosphate (according to UniProt)

Protein family

• ABC transporter superfamily (according to UniProt)

Domains

• ABC transporter domain (aa 2-237) (according to UniProt)

Structure

• 1VPL (PDB) (from Thermotoga maritima, 38% identity)
• P46903 (AlphaFold)

Localization

• membrane associated (via NatB) PubMed

Expression and Regulation

Operons

• Genes: natA-natB

  Description: PubMed

  Regulatory mechanism

  • NatR: activation, PubMed, in natR regulon

Biological materials

Mutant

• BKE02750 (ΔnatA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTCACAATCTCCCTTAT,  downstream forward: _UP4_AAGCTTGTCAGGGGGATTTC
• BKK02750 (ΔnatA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTCACAATCTCCCTTAT,  downstream forward: _UP4_AAGCTTGTCAGGGGGATTTC

References

Loading