HmoA

• Description: heme monooxygenase
  
  

Gene name	hmoA
Synonyms	yetG
Essential	no
Product	heme monooxygenase
Function	degradation of heme
Gene expression levels in SubtiExpress: hmoA
Metabolic function and regulation of this protein in SubtiPathways: HmoA
MW, pI	14 kDa, 9.126
Gene length, protein length	375 bp, 125 aa
Immediate neighbours	yetF, yetH
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

acquisition of iron

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

• Locus tag: BSU07150

Database entries

• BsubCyc: BSU07150

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: binds hemin in vitro with ~1:1 stoichiometry and degrade hemin in the presence of an electron donor PubMed

• Protein family: antibiotic biosynthesis monooxygenase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU07150

• Structure:

• UniProt: O31534

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: hmoA (based on genomic context)

• Expression browser: hmoA PubMed

• Sigma factor:

• Regulation:
  • induced by iron limitation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional references: PubMed