albE

168

antilisterial bacteriocin (subtilosin) production

Locus: BSU_37410

Molecular weight: 43.20 kDa

Isoelectric point: 6.07

Protein length: 386 aa

Gene length: 1161 bp

Function: antilisterial bacteriocin (subtilosin) production

Product: processing protease

Essential: no

E.C.: null

Synonyms: albE, ywhO

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0612 (Galperin et al., 2021)

Gene

Coordinates: 3,839,852  3,841,012

The protein

Structure

• 7Y8U (PDB) (AlbE-AlbF complex from Quasibacillus thermotolerans) PubMed
• P71007 (AlphaFold)

Expression and Regulation

Operons

• Genes: sboA-sboX-albA-albB-albC-albD-albE-albF-albG

  Description: PubMed

  Regulation

  • expressed under anaerobic conditions (ResD) PubMed

  Expression

  • expression is heterogeneous PubMed

  Regulatory mechanism

  • Rok: repression, PubMed, in rok regulon
  • ResD: activation, PubMed, in resD regulon
  • AbrB: repression, PubMed, in abrB regulon

  Sigma factors

  • SigA: sigma factor, PubMed, in sigA regulon

Biological materials

Mutant

• MGNA-A527 (ywhO::erm), available at the NBRP B. subtilis, Japan
• BKE37410 (albE::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGAAAATTGATGAGTCTTCA,  downstream forward: _UP4_GCTCATGTAGTAAGGGGATG
• BKK37410 (albE::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGAAAATTGATGAGTCTTCA,  downstream forward: _UP4_GCTCATGTAGTAAGGGGATG

References

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