yvdR

168

similar to multidrug-efflux transporter

Locus: BSU_34500

Molecular weight: 11.29 kDa

Isoelectric point: 9.06

Protein length: 106 aa

Gene length: 321 bp

Function: unknown

Product: subunit of unidentified multidrug transporter

Essential: no

Synonyms: yvdR

Genomic Context

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Categories containing this gene/protein

Cellular processes, Transporters, Transporters/ other, Multidrug exporters

Information processing, Protein synthesis, modification and degradation, Chaperone/ protein folding/ based on similarity

Groups of genes, Membrane proteins

List of homologs in different organisms, belongs to COG2076 (Galperin et al., 2021)

Gene

Coordinates: 3,541,823  3,542,143

The protein

Protein family

paired small multidrug resistance  protein family (PSMR family) PubMed
drug/metabolite transporter (DMT) superfamily (according to UniProt)
Small multidrug resistance (SMR) (TC 2.A.7.1) family (according to UniProt)

Structure

3B5D (PDB) (E. coli EmrE, 33% identity) PubMed
O06999 (AlphaFold)

Localization

cell membrane (according to UniProt)

Expression and Regulation

Operons

Genes: yvdT-yvdS-yvdR

Description: PubMed

Biological materials

Mutant

MGNA-B618 (yvdR::erm), available at the NBRP B. subtilis, Japan
BKE34500 (yvdR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTATTTTTCACCTCCCGG,  downstream forward: _UP4_TAAAATCAAGGCATATACAG
BKK34500 (yvdR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTATTTTTCACCTCCCGG,  downstream forward: _UP4_TAAAATCAAGGCATATACAG

References

Research papers

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