yvfR

168

similar to ABC transporter (ATP-binding protein)

Locus: BSU_34090

Molecular weight: 33.63 kDa

Isoelectric point: 6.17

Protein length: 301 aa

Gene length: 906 bp

Function: unknown

Product: ABC transporter (ATP-binding protein)

Essential: no

Synonyms: yvfR

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG1131 (Galperin et al., 2021)

Gene

Coordinates: 3,498,352 → 3,499,257

The protein

Protein family

• ABC transporter superfamily (according to UniProt)

Domains

• ABC transporter domain (aa 6-230) (according to UniProt)

Structure

• 4YER (PDB) (from Thermotoga maritima, 32% identity)
• O07016 (AlphaFold)

Localization

• plasma membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: yvfR-yvfS

  Description: PubMed

  Regulatory mechanism

  • DesR: transcription activation, DesR activates transcription in the non-phosphorylated state at 37°C PubMed, in desR regulon
  • YvfU: transcription activation, PubMed, in yvfU regulon

Biological materials

Mutant

• MGNA-A481 (yvfR::erm), available at the NBRP B. subtilis, Japan
• BKE34090 (ΔyvfR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACATGAGCACCTCCTGATC,  downstream forward: _UP4_GACGGCAACAGGGAGGCGAT
• BKK34090 (ΔyvfR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACATGAGCACCTCCTGATC,  downstream forward: _UP4_GACGGCAACAGGGAGGCGAT

References

Loading