yvfS

168

similar to ABC transporter (transmembrane subunit)

Locus: BSU_34080

Molecular weight: 27.78 kDa

Isoelectric point: 9.76

Protein length: 245 aa

Gene length: 738 bp

Function: unknown

Product: ABC transporter (transmembrane subunit)

Essential: no

Synonyms: yvfS

Genomic Context

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List of homologs in different organisms, belongs to COG0842 (Galperin et al., 2021)

Gene

Coordinates: 3,497,614  3,498,351

The protein

Protein family

• ABC-2 integral membrane protein family (according to UniProt)

Domains

• ABC transmembrane type-2 domain (aa 20-242) (according to UniProt)

Structure

• O07017 (AlphaFold)

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: yvfR-yvfS

  Description: PubMed

  Regulatory mechanism

  • DesR: transcription activation, DesR activates transcription in the non-phosphorylated state at 37°C PubMed, in desR regulon
  • YvfU: transcription activation, PubMed, in yvfU regulon

Biological materials

Mutant

• MGNA-A482 (yvfS::erm), available at the NBRP B. subtilis, Japan
• BKE34080 (yvfS::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GCTTTGCTTTTGCAGCACGT,  downstream forward: _UP4_AGAAAACAAGAAGCGGTGTA
• BKK34080 (yvfS::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GCTTTGCTTTTGCAGCACGT,  downstream forward: _UP4_AGAAAACAAGAAGCGGTGTA

References

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