yvgJ

168

lipoteichoic acid synthesis primase

Locus: BSU_33360

Molecular weight: 70.57 kDa

Isoelectric point: 5.31

Protein length: 617 aa

Gene length: 1854 bp

Function: biosynthesis of lipoteichoic acid

Product: lipoteichoic acid synthesis primase

Essential: no

Synonyms: yvgJ, yvsF

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG1368 (Galperin et al., 2021)

Gene

Coordinates: 3,422,354  3,424,207

The protein

Protein family

• LTA synthase family (according to UniProt)

Structure

• 2W5Q (PDB) (LtaS from S. aureus, corresponds to aa 215 ... 615 of YvgJ) PubMed
• O32206 (AlphaFold)

Modification

• can be phosphorylated by PrkC in vitro PubMed

Paralogous protein(s)

• YfnI, YqgS, LtaS

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: yvgJ

  Description: PubMed

Biological materials

Mutant

• MGNA-B065 (yvgJ::erm), available at the NBRP B. subtilis, Japan
• BKE33360 (yvgJ::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCAATATGACTCCTCACG,  downstream forward: _UP4_TGAAAAAATCCCTCTATCAA
• BKK33360 (yvgJ::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCAATATGACTCCTCACG,  downstream forward: _UP4_TGAAAAAATCCCTCTATCAA

References

Reviews

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Original Publications

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