paiB

168

transcriptional repressor of sporulation and degradative enzyme genes

Locus: BSU_32140

Molecular weight: 23.96 kDa

Isoelectric point: 5.03

Protein length: 207 aa

Gene length: 624 bp

Function: regulation of sporulation, degradative enzyme and motility genes

Product: transcriptional repressor

Essential: no

Synonyms: paiB, yumE

Genomic Context

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List of homologs in different organisms, belongs to COG2808 (Galperin et al., 2021)

Gene

Coordinates: 3,304,096  3,304,719

The protein

Protein family

• paiB family (single member, according to UniProt)

Structure

• 2OL5 (PDB) (from Geobacillus stearothermophilus, 39% identity) PubMed
• P21341 (AlphaFold)

Expression and Regulation

Operons

• Genes: paiA-paiB

  Description: PubMed

Biological materials

Mutant

• MGNA-A088 (paiB::erm), available at the NBRP B. subtilis, Japan
• BKE32140 (paiB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCATCATCCACCCTTCGA,  downstream forward: _UP4_TAAGCTTACTTTGCTGAAGA
• BKK32140 (paiB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCATCATCCACCCTTCGA,  downstream forward: _UP4_TAAGCTTACTTTGCTGAAGA

References

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