ytlA

168

similar to ABC transporter (binding protein)

Locus: BSU_30595

Molecular weight: 38.00 kDa

Isoelectric point: 4.998

Protein length: 334 aa

Gene length: 1005 bp

Function: unknown

Product: putative ABC transporter (binding protein)

Essential: no

Synonyms: ytlA

Genomic Context

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List of homologs in different organisms, belongs to COG0715 (Galperin et al., 2021)

Gene

Coordinates: 3,132,370  3,133,374

The protein

Protein family

• bacterial solute-binding protein SsuA/TauA family (with SsuA, according to Uniprot)

Structure

• 3QSL (PDB) (from Bordetella sp., 26% identity)
• C0SP84 (AlphaFold)

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: ytlA-ytlC-ytlD

  Description: PubMed

  Regulation

  • expressed late during sporulation in the mother cell (SigK) PubMed

  Sigma factors

  • SigK: sigma factor, PubMed, in sigK regulon

Biological materials

Mutant

• MGNA-A301 (ytlA::erm), available at the NBRP B. subtilis, Japan
• BKE30595 (ytlA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACATAGACAACCTCCTTAT,  downstream forward: _UP4_TCGGAGAAATAGGAGGCGCC
• BKK30595 (ytlA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACATAGACAACCTCCTTAT,  downstream forward: _UP4_TCGGAGAAATAGGAGGCGCC

References

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