nusB

nusB
168

transcription antitermination factor

Locus
BSU_24320
Molecular weight
14.74 kDa
Isoelectric point
4.76
Protein length
Gene length
Function
stable RNA transcription
Product
antitermination factor
Essential
no
Synonyms
nusB, yqhZ

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0781 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,529,267  2,529,662
The protein
Protein family
nusB family (single member, according to UniProt)
Structure
1EYV (PDB) (from Mycobacterium tuberculosis, 40% identity) PubMed
3R2C (PDB) (the NusB-RpsJ complex from Aquifex aeolicus) PubMed
Expression and Regulation
Operons
Genes
Description
Regulation
repressed in the presence of purine nucleotides (PurR) PubMed
Regulatory mechanism
PurR: repression, (molecular inducer: PRPP) PubMed, in purR regulon
stringent response: negative regulation, in stringent response
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nusBfolD

2025-07-05 04:21:01

ghost

100

c4252d054332d8a4aedfc8005fc5ac765b3f1223

9765ECDFA2520F690845D25E096C6F679262B232

Biological materials
Mutant
MGNA-C368 (yqhZ::erm), available at the NBRP B. subtilis, Japan
BKE24320 (nusB::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATTTTCTTTCTCCTTTGAT,  downstream forward: _UP4_TAGGAGGAAAGAAAATGACT
BKK24320 (nusB::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATTTTCTTTCTCCTTTGAT,  downstream forward: _UP4_TAGGAGGAAAGAAAATGACT
References
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Page visits: 4733

Time of last update: 2025-07-06 05:23:20

Author of last update: Jstuelk