aprX

aprX
168

intracellular alkaline serine protease

Locus
BSU_17260
Molecular weight
47.74 kDa
Isoelectric point
4.97
Protein length
Gene length
Function
protein degradation
Product
intracellular alkaline serine protease
Essential
no
Synonyms
aprX

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1404 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,861,384  1,862,712
The protein
Protein family
peptidase S8 family (according to UniProt)
Peptidase S8 domain (aa 122-439) (according to UniProt)
Structure
3WHI (PDB) (AprE, corresponds to aa 78 ... 436, 33% identity) PubMed
Expression and Regulation
Operons
Genes
Description
Regulation
induced by DNA damage (LexA) PubMed
Regulatory mechanism
LexA: repression, PubMed, in lexA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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aprX

2025-06-23 13:18:14

Jstuelk

115

31d056fdbc6d6278981e708ff8be8d60f025b0fb

C80B550023CBA5C0D32374396F9A0E306850B8E0

Biological materials
Mutant
MGNA-A019 (aprX::erm), available at the NBRP B. subtilis, Japan
BKE17260 (aprX::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGTATTTTCCTCCTATTA,  downstream forward: _UP4_TAAACATCATCAAAAGCCGG
BKK17260 (aprX::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGTATTTTCCTCCTATTA,  downstream forward: _UP4_TAAACATCATCAAAAGCCGG
References
Reviews
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Original Publications
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Labs working on this gene/protein
Alessandra Albertini, University of Pavia, Italy homepage

945A1332A020CF842DA590589C88C758DE65C84E

Page visits: 3990

Time of last update: 2025-07-03 16:57:47

Author of last update: Jstuelk