Difference between revisions of "IspC"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU16550&redirect=T BSU16550] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU16550&redirect=T BSU16550] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=1R0K 1R0K] (from ''Zymomonas mobilis'', 45% identity) {{PubMed|15063313}} | * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=1R0K 1R0K] (from ''Zymomonas mobilis'', 45% identity) {{PubMed|15063313}} | ||
Revision as of 13:45, 2 April 2014
- Description: 1-deoxy-D-xylulose-5-phosphate reductoisomerase, second step in the MEP pathway of isoprenoid biosynthesis
| Gene name | ispC |
| Synonyms | yluB, dxr |
| Essential | yes PubMed |
| Product | 1-deoxy-D-xylulose-5-phosphate reductoisomerase |
| Function | MEP pathway of isoprenoid biosynthesis |
| Gene expression levels in SubtiExpress: ispC | |
| MW, pI | 43 kDa, 5.801 |
| Gene length, protein length | 1164 bp, 388 aa |
| Immediate neighbours | cdsA, rasP |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
biosynthesis of lipids, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU16550
Phenotypes of a mutant
essential PubMed
Database entries
- BsubCyc: BSU16550
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + NADPH (according to Swiss-Prot)
- Protein family: DXR family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU16550
- UniProt: O31753
- KEGG entry: [2]
- E.C. number: 1.1.1.267
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
