Difference between revisions of "RecG"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15870&redirect=T BSU15870] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
| Line 95: | Line 96: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15870&redirect=T BSU15870] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1GM5 1GM5] (from ''Thermotoga maritima'', 43% identity, 62% similarity) | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1GM5 1GM5] (from ''Thermotoga maritima'', 43% identity, 62% similarity) | ||
Revision as of 13:42, 2 April 2014
- Description: ATP-dependent DNA helicase, branch migration translocase, required for DNA repair and chromosomal segregation
| Gene name | recG |
| Synonyms | ylpB |
| Essential | no |
| Product | ATP-dependent DNA helicase, branch migration translocase |
| Function | DNA repair and chromosomal segregation |
| Gene expression levels in SubtiExpress: recG | |
| Interactions involving this protein in SubtInteract: RecG | |
| Metabolic function and regulation of this protein in SubtiPathways: recG | |
| MW, pI | 77 kDa, 7.093 |
| Gene length, protein length | 2046 bp, 682 aa |
| Immediate neighbours | sdaAA, fapR |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15870
Phenotypes of a mutant
Database entries
- BsubCyc: BSU15870
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: helicase C-terminal domain (according to Swiss-Prot)
- Paralogous protein(s): Mfd
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU15870
- Structure: 1GM5 (from Thermotoga maritima, 43% identity, 62% similarity)
- UniProt: O34942
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
François Lecointe, Céline Sérèna, Marion Velten, Audrey Costes, Stephen McGovern, Jean-Christophe Meile, Jeffrey Errington, S Dusko Ehrlich, Philippe Noirot, Patrice Polard
Anticipating chromosomal replication fork arrest: SSB targets repair DNA helicases to active forks.
EMBO J: 2007, 26(19);4239-51
[PubMed:17853894]
[WorldCat.org]
[DOI]
(P p)
Humberto Sanchez, Begoña Carrasco, M Castillo Cozar, Juan C Alonso
Bacillus subtilis RecG branch migration translocase is required for DNA repair and chromosomal segregation.
Mol Microbiol: 2007, 65(4);920-35
[PubMed:17640277]
[WorldCat.org]
[DOI]
(P p)
Qin Wen, Akeel A Mahdi, Geoffrey S Briggs, Gary J Sharples, Robert G Lloyd
Conservation of RecG activity from pathogens to hyperthermophiles.
DNA Repair (Amst): 2005, 4(1);23-31
[PubMed:15533834]
[WorldCat.org]
[DOI]
(P p)
Additional publications: PubMed
