ylxX

168

unknown

Locus: BSU_15260

Molecular weight: 26.35 kDa

Isoelectric point: 8.97

Protein length: 235 aa

Gene length: 708 bp

Function: unknown

Product: unknown

Essential: no

Synonyms: ylxX

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG3879 (Galperin et al., 2021)

Gene

Coordinates: 1,595,210  1,595,917

The protein

Protein family

• UPF0749 family (with YlxW, according to UniProt)

Structure

• Q45544 (AlphaFold)

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: murG-murB-divIB-ylxW-ylxX-sbp

  Description: PubMed

  Regulation

  • expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell (SigE) PubMed

  Regulatory mechanism

  • SpoIIID: repression, PubMed, in spoIIID regulon

  Sigma factors

  • SigM: sigma factor, (promoter within MurG) PubMed, in sigM regulon
  • SigA: sigma factor, PubMed, in sigA regulon
  • SigE: sigma factor, PubMed, in sigE regulon

• Genes: murE-mraY-murD-spoVE-murG-murB-divIB-ylxW-ylxX-sbp

  Description: PubMed

  Regulation

  • expressed during vegatative growth PubMed

  Regulatory mechanism

  • stringent response: negative regulation, in stringent response
  • SpoIIID: repression, PubMed, in spoIIID regulon

  Sigma factors

  • SigE: sigma factor, PubMed, in sigE regulon

• Genes: spoVE-murG-murB-divIB-ylxW-ylxX-sbp

  Description: PubMed

  Regulation

  • expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell (SigE) PubMed

• Genes: divIB-ylxW-ylxX-sbp

  Description: PubMed

• Genes: murB-divIB-ylxW-ylxX-sbp

  Description: PubMed

  Regulation

  • expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell (SigE) PubMed

Additional information

• translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

Mutant

• MGNA-B362 (ylxX::erm), available at the NBRP B. subtilis, Japan
• BKE15260 (ylxX::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATCTATTTCACCCGCTTT,  downstream forward: _UP4_GACTGAAAAGGAGGAGAATT
• BKK15260 (ylxX::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATCTATTTCACCCGCTTT,  downstream forward: _UP4_GACTGAAAAGGAGGAGAATT

References

Reviews

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Original Publications

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