Difference between revisions of "PbpB"

From SubtiWiki
Jump to: navigation, search
(References)
Line 61: Line 61:
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15160&redirect=T BSU15160]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yllB-ylxA-ftsL-pbpB.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yllB-ylxA-ftsL-pbpB.html]
Line 103: Line 104:
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15160&redirect=T BSU15160]
  
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=1rp5 1RP5] (PBP 2x from ''Streptococcus pneumoniae'', 32% identity) {{PubMed|14734544}}
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=1rp5 1RP5] (PBP 2x from ''Streptococcus pneumoniae'', 32% identity) {{PubMed|14734544}}

Revision as of 13:38, 2 April 2014

Gene name pbpB
Synonyms
Essential yes PubMed
Product penicillin-binding protein 2B
Function septation, cell division
Gene expression levels in SubtiExpress: pbpB
Interactions involving this protein in SubtInteract: PbpB
MW, pI 79 kDa, 9.234
Gene length, protein length 2148 bp, 716 aa
Immediate neighbours ftsL, spoVD
Sequences Protein DNA DNA_with_flanks
Genetic context
PbpB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PbpB expression.png















Categories containing this gene/protein

cell wall synthesis, cell division, essential genes, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15160

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: transpeptidase family (according to Swiss-Prot)
  • Paralogous protein(s): SpoVD

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure: 1RP5 (PBP 2x from Streptococcus pneumoniae, 32% identity) PubMed
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • constitutively expressed PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Jeff Errington lab
  • Antibody:

Labs working on this gene/protein

Jeff Errington, Newcastle University, UK homepage

Your additional remarks

References