yknZ

168

ABC transporter (permease) for the export of the SdpC toxin

Locus: BSU_14370

Molecular weight: 41.96 kDa

Isoelectric point: 4.68

Protein length: 397 aa

Gene length: 1194 bp

Function: resistence against SdpC toxin

Product: ABC transporter (permease)

Essential: no

Synonyms: yknZ

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0577 (Galperin et al., 2021)

Gene

Coordinates: 1,506,105  1,507,298

The protein

Protein family

• ABC-4 integral membrane protein family (according to UniProt)

Structure

• 5WS4 (PDB) (from Acinetobacter baumanni, 38% identity) PubMed
• O31712 (AlphaFold)

Paralogous protein(s)

• YvrN

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: yknU-yknV-yknW-yknX-yknY-yknZ

  Description: PubMed

• Genes: yknW-yknX-yknY-yknZ

  Description: PubMed

  Regulation

  • repressed during logrithmic growth (AbrB) PubMed

  Regulatory mechanism

  • AbrB: repression, PubMed, in abrB regulon

  Sigma factors

  • SigW: sigma factor, PubMed, in sigW regulon

Biological materials

Mutant

• MGNA-B351 (yknZ::erm), available at the NBRP B. subtilis, Japan
• BKE14370 (yknZ::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCTGATGTTTTCCAACA,  downstream forward: _UP4_TAGCCTCATGCAACATGCAT
• BKK14370 (yknZ::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCTGATGTTTTCCAACA,  downstream forward: _UP4_TAGCCTCATGCAACATGCAT

References

Loading