splA

168

transcriptional repressor of the spore photoproduct lyase splA-splB operon

Locus: BSU_13920

Molecular weight: 9.08 kDa

Isoelectric point: 4.42

Protein length: 79 aa

Gene length: 240 bp

Function: regulation of the splA-splB operon

Product: transcriptional regulator

Essential: no

Synonyms: splA, ykxI

Genomic Context

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List of homologs in different organisms

Gene

Coordinates: 1,461,453  1,461,692

The protein

Structure

• P37955 (AlphaFold)

Expression and Regulation

Operons

• Genes: splA-splB

  Description: PubMed

  Regulation

  • expressed during sporulation in the forespore (SigG) PubMed

  Regulatory mechanism

  • SplA: negative autoregulation, in splA regulon

  Sigma factors

  • SigG: sigma factor, PubMed, in sigG regulon

Biological materials

Mutant

• BKE13920 (splA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACTATCCCTCCTAGCCA,  downstream forward: _UP4_TAACAAGGAAATCATTACAA
• BKK13920 (splA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACTATCCCTCCTAGCCA,  downstream forward: _UP4_TAACAAGGAAATCATTACAA

References

Reviews

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Original Publications

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Structure of the spore photoproduct lesion in DNA

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