cotT

168

spore coat protein (inner)

Locus: BSU_12090

Molecular weight: 12.85 kDa

Isoelectric point: 9.47

Protein length: 107 aa

Gene length: 324 bp

Function: resistance of the spore

Product: spore coat protein (inner)

Essential: no

E.C.: null

Synonyms: cotT

Genomic Context

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List of homologs in different organisms

Gene

Coordinates: 1,280,626  1,280,949

The protein

Structure

• P11863 (AlphaFold)

Localization

• inner spore coat, localization depends on SafA  PubMed

Expression and Regulation

Operons

• Genes: cotT

  Description: PubMed

  Regulation

  • expressed during sporulation in the mother cell (SigE, SigK, GerE, SpoIIID) PubMed

  Regulatory mechanism

  • SpoIIID: activation, PubMed, in spoIIID regulon
  • GerE: repression, PubMed, in gerE regulon

  Sigma factors

  • SigK: sigma factor, PubMed, in sigK regulon
  • SigE: sigma factor, PubMed, in sigE regulon

Biological materials

Mutant

• 1S108 ( cotT::cat), PubMed, available at BGSC
• BKE12090 (cotT::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAGAGGAAAACCTCCCTAG,  downstream forward: _UP4_TAGTCGCCACATATCAAAAT
• BKK12090 (cotT::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAGAGGAAAACCTCCCTAG,  downstream forward: _UP4_TAGTCGCCACATATCAAAAT

Labs working on this gene/protein

• Arthur Aronson, Purdue University, West Lafayette, USA homepage

References

Reviews

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Original Publications

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