yitG

168

similar to multidrug resistance protein

Locus: BSU_10980

Molecular weight: 45.35 kDa

Isoelectric point: 9.74

Protein length: 422 aa

Gene length: 1269 bp

Function: unknown

Product: unknown

Essential: no

Synonyms: yitG

Genomic Context

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Categories containing this gene/protein

Cellular processes, Transporters, Transporters/ other, Other transporters

Lifestyles, Sporulation, Sporulation proteins, Sporulation proteins/ other

Lifestyles, Coping with stress, Resistance against toxins/ antibiotics/ based on similarity

Groups of genes, Efp-dependent proteins

Groups of genes, Membrane proteins

List of homologs in different organisms, belongs to COG2814 (Galperin et al., 2021)

Gene

Coordinates: 1,175,985 → 1,177,253

The protein

Protein family

major facilitator superfamily (according to UniProt)

Structure

Q796Q1 (AlphaFold)

Localization

cell membrane (according to UniProt)

Expression and Regulation

Operons

Genes: yitG-yitF

Description: PubMed

Regulation

expressed during sporulation in the forespore (SigG) PubMed

Sigma factors

SigG: sigma factor, PubMed, in sigG regulon

Additional information

translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

Mutant

MGNA-B181 (yitG::erm), available at the NBRP B. subtilis, Japan
BKE10980 (ΔyitG::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTCAGAGCACACTCCTT,  downstream forward: _UP4_GCTGAGGAAAGGTAGCACCC
BKK10980 (ΔyitG::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTCAGAGCACACTCCTT,  downstream forward: _UP4_GCTGAGGAAAGGTAGCACCC

References

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