GerPA

• Description: spore germination protein, facilitates access of nutrient germinants to their cognate germinant receptors in spores’ inner membrane
  
  

Gene name	gerPA
Synonyms	yisH
Essential	no
Product	unknown
Function	germination
Gene expression levels in SubtiExpress: gerPA
MW, pI	7 kDa, 4.464
Gene length, protein length	219 bp, 73 aa
Immediate neighbours	gerPB, yisI
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

germination

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

• Locus tag: BSU10720

Database entries

• BsubCyc: BSU10720

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: gerPA/gerPF family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU10720

• Structure:

• UniProt: O06721

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gerPA-gerPB-gerPC-gerPD-gerPE-gerPF (according to DBTBS)

• Expression browser: gerPA PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed during sporulation in the mother cell (SigK) PubMed
  • subject to negative regulation by GerE PubMed

• Regulatory mechanism:

• Additional information:
  • A ncRNA is predicted between gerPA and yisI PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

J Behravan, H Chirakkal, A Masson, A Moir
Mutations in the gerP locus of Bacillus subtilis and Bacillus cereus affect access of germinants to their targets in spores.
J Bacteriol: 2000, 182(7);1987-94
[PubMed:10715007] [WorldCat.org] [DOI] (P p)