glcP

168

probable glucose/mannose:H⁺ symporter

Locus: BSU_10520

Molecular weight: 44.75 kDa

Isoelectric point: 8.77

Protein length: 401 aa

Gene length: 1206 bp

Function: unknown

Product: probable glucose/mannose:H⁺ symporter

Essential: no

Synonyms: glcP, yhjI

Genomic Context

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List of homologs in different organisms, belongs to COG0738 (Galperin et al., 2021)

Gene

Coordinates: 1,125,123  1,126,328

The protein

Protein family

• major facilitator superfamily (according to UniProt)

Structure

• O07563 (AlphaFold)

Expression and Regulation

Operons

• Genes: ntdA-ntdB-ntdC-glcP

  Description: PubMed

  Regulation

  • induced by 3,3'-neotrehalosadiamine and kanosamine (NtdR) PubMed

  Regulatory mechanism

  • NtdR: activation , in ntdR regulon

  Sigma factors

  • SigA: sigma factor, PubMed, in sigA regulon

Biological materials

Mutant

• MGNA-A723 (yhjI::erm), available at the NBRP B. subtilis, Japan
• BKE10520 (glcP::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCATTACACCCCTATAT,  downstream forward: _UP4_TAGAAAACGTATAAAATAAA
• BKK10520 (glcP::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCATTACACCCCTATAT,  downstream forward: _UP4_TAGAAAACGTATAAAATAAA

References

Reviews

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Original Publications

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