fluC

168

flouride exporter (together with YhdV)

Locus: BSU_09600

Molecular weight: 12.31 kDa

Isoelectric point: 9.85

Protein length: 118 aa

Gene length: 357 bp

Function: export of flouride

Product: flouride channel

Essential: no

Synonyms: fluC, yhdU, crcBA

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0239 (Galperin et al., 2021)

Gene

Coordinates: 1,036,953  1,037,309

Phenotypes of a mutant

• very sensitive to flouride PubMed

The protein

Protein family

• CrcB (TC 9.B.71) family, (together with YhdV, according to UniProt)

Structure

• 5A40 (PDB) (from Bordetella pertussis, 41% identity, aa 7 ... 87) PubMed
• O07590 (AlphaFold)

Paralogous protein(s)

• YhdV

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: yhdW-yhdV-fluC

  Description: PubMed

Biological materials

Mutant

• MGNA-B486 (yhdU::erm), available at the NBRP B. subtilis, Japan
• BKE09600 (fluC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CCCTATGAAAATACCCGCTA,  downstream forward: _UP4_ATCACAATATAAAAAAACCT
• BKK09600 (fluC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CCCTATGAAAATACCCGCTA,  downstream forward: _UP4_ATCACAATATAAAAAAACCT

References

Reviews

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Research papers

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