glpP

168

transcriptional antiterminator of the glpT-glpQ and glpF-glpK-glpD operons

Locus: BSU_09270

Molecular weight: 21.46 kDa

Isoelectric point: 8.1

Protein length: 192 aa

Gene length: 579 bp

Function: regulation of glycerol and glycerol-3-phosphate utilization

Product: transcriptional antiterminator

Essential: no

Synonyms: glpP

Genomic Context

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List of homologs in different organisms, belongs to COG1954 (Galperin et al., 2021)

Gene

Coordinates: 1,001,744  1,002,322

The protein

Structure

• 3KTS (PDB) (from Listeria monocytogenes, 49% identity)
• P30300 (AlphaFold)

Expression and Regulation

Operons

• Genes: yhxA-glpP

  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in sigA regulon

  Additional information

  • half-life of the mRNA: 3.7 min PubMed
  • half-life of the mRNA: 3.7 min PubMed

Biological materials

Mutant

• BKE09270 (glpP::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTGCTCCTTTAATAATT,  downstream forward: _UP4_TGACACCGCTTTCATGCACT
• BKK09270 (glpP::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTGCTCCTTTAATAATT,  downstream forward: _UP4_TGACACCGCTTTCATGCACT

Labs working on this gene/protein

• Josef Deutscher, Paris-Grignon, France

References

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