Difference between revisions of "SigH"

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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00980&redirect=T BSU00980]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sigH.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sigH.html]
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00980&redirect=T BSU00980]
  
 
* '''Structure:'''
 
* '''Structure:'''

Revision as of 12:48, 2 April 2014

Gene name sigH
Synonyms spo0H
Essential no
Product RNA polymerase sigma factor SigH
Function transcription of early stationary phase genes
(sporulation, competence)
Gene expression levels in SubtiExpress: sigH
Interactions involving this protein in SubtInteract: SigH
MW, pI 25 kDa, 5.146
Gene length, protein length 654 bp, 218 aa
Immediate neighbours yacP, rpmGB
Sequences Protein DNA DNA_with_flanks
Genetic context
SigH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SigH expression.png

























Categories containing this gene/protein

transcription, sigma factors and their control

This gene is a member of the following regulons

AbrB regulon

The SigH regulon

The gene

Basic information

  • Locus tag: BSU00980

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: sigma-70 factor family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: sigH (DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Michiel J L de Hoon, Patrick Eichenberger, Dennis Vitkup
Hierarchical evolution of the bacterial sporulation network.
Curr Biol: 2010, 20(17);R735-45
[PubMed:20833318] [WorldCat.org] [DOI] (I p)

The SigH regulon

Robert A Britton, Patrick Eichenberger, Jose Eduardo Gonzalez-Pastor, Paul Fawcett, Rita Monson, Richard Losick, Alan D Grossman
Genome-wide analysis of the stationary-phase sigma factor (sigma-H) regulon of Bacillus subtilis.
J Bacteriol: 2002, 184(17);4881-90
[PubMed:12169614] [WorldCat.org] [DOI] (P p)

Original Publications

Imke G de Jong, Jan-Willem Veening, Oscar P Kuipers
Heterochronic phosphorelay gene expression as a source of heterogeneity in Bacillus subtilis spore formation.
J Bacteriol: 2010, 192(8);2053-67
[PubMed:20154131] [WorldCat.org] [DOI] (I p)

C Eymann, M Hecker
Induction of sigma(B)-dependent general stress genes by amino acid starvation in a spo0H mutant of Bacillus subtilis.
FEMS Microbiol Lett: 2001, 199(2);221-7
[PubMed:11377871] [WorldCat.org] [DOI] (P p)

C M Buckner, C P Moran
A region in Bacillus subtilis sigmaH required for Spo0A-dependent promoter activity.
J Bacteriol: 1998, 180(18);4987-90
[PubMed:9733708] [WorldCat.org] [DOI] (P p)

P A Levin, R Losick
Transcription factor Spo0A switches the localization of the cell division protein FtsZ from a medial to a bipolar pattern in Bacillus subtilis.
Genes Dev: 1996, 10(4);478-88
[PubMed:8600030] [WorldCat.org] [DOI] (P p)

M A Strauch
Delineation of AbrB-binding sites on the Bacillus subtilis spo0H, kinB, ftsAZ, and pbpE promoters and use of a derived homology to identify a previously unsuspected binding site in the bsuB1 methylase promote.
J Bacteriol: 1995, 177(23);6999-7002
[PubMed:7592498] [WorldCat.org] [DOI] (P p)

T Bird, D Burbulys, J J Wu, M A Strauch, J A Hoch, G B Spiegelman
The effect of supercoiling on the in vitro transcription of the spoIIA operon from Bacillus subtilis.
Biochimie: 1992, 74(7-8);627-34
[PubMed:1391042] [WorldCat.org] [DOI] (P p)

J Healy, J Weir, I Smith, R Losick
Post-transcriptional control of a sporulation regulatory gene encoding transcription factor sigma H in Bacillus subtilis.
Mol Microbiol: 1991, 5(2);477-87
[PubMed:1904128] [WorldCat.org] [DOI] (P p)

J Weir, M Predich, E Dubnau, G Nair, I Smith
Regulation of spo0H, a gene coding for the Bacillus subtilis sigma H factor.
J Bacteriol: 1991, 173(2);521-9
[PubMed:1898930] [WorldCat.org] [DOI] (P p)

D Daniels, P Zuber, R Losick
Two amino acids in an RNA polymerase sigma factor involved in the recognition of adjacent base pairs in the -10 region of a cognate promoter.
Proc Natl Acad Sci U S A: 1990, 87(20);8075-9
[PubMed:2122453] [WorldCat.org] [DOI] (P p)

U Bai, M Lewandoski, E Dubnau, I Smith
Temporal regulation of the Bacillus subtilis early sporulation gene spo0F.
J Bacteriol: 1990, 172(9);5432-9
[PubMed:2118512] [WorldCat.org] [DOI] (P p)

K M Tatti, H L Carter, A Moir, C P Moran
Sigma H-directed transcription of citG in Bacillus subtilis.
J Bacteriol: 1989, 171(11);5928-32
[PubMed:2509422] [WorldCat.org] [DOI] (P p)

K J Jaacks, J Healy, R Losick, A D Grossman
Identification and characterization of genes controlled by the sporulation-regulatory gene spo0H in Bacillus subtilis.
J Bacteriol: 1989, 171(8);4121-9
[PubMed:2502532] [WorldCat.org] [DOI] (P p)

P Zuber, J Healy, H L Carter, S Cutting, C P Moran, R Losick
Mutation changing the specificity of an RNA polymerase sigma factor.
J Mol Biol: 1989, 206(4);605-14
[PubMed:2500529] [WorldCat.org] [DOI] (P p)

H L Carter, L F Wang, R H Doi, C P Moran
rpoD operon promoter used by sigma H-RNA polymerase in Bacillus subtilis.
J Bacteriol: 1988, 170(4);1617-21
[PubMed:3127379] [WorldCat.org] [DOI] (P p)

C Ray, M Igo, W Shafer, R Losick, C P Moran
Suppression of ctc promoter mutations in Bacillus subtilis.
J Bacteriol: 1988, 170(2);900-7
[PubMed:3123466] [WorldCat.org] [DOI] (P p)

P Zuber, R Losick
spoOH: a developmental regulatory gene for promoter utilization in Bacillus subtilis.
Cold Spring Harb Symp Quant Biol: 1985, 50;483-8
[PubMed:3007003] [WorldCat.org] [DOI] (P p)

W C Johnson, C P Moran, R Losick
Two RNA polymerase sigma factors from Bacillus subtilis discriminate between overlapping promoters for a developmentally regulated gene.
Nature: 1983, 302(5911);800-4
[PubMed:6405278] [WorldCat.org] [DOI] (P p)