Difference between revisions of "Fin"
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| − | * '''Description:''' | + | * '''Description:''' |
| − | + | ** suppressor of ''[[recU]]'' mutations, participates in the stabilization and or processing of holliday junction intermediates {{PubMed|11810266}}<br/> | |
| + | ** alternative description: antagonist to [[SigF]], required for the switch from [[SigF]]- to [[SigG]]-dependent gene expression in the forespore {{PubMed|21037003}}<br/><br/> | ||
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || unknown | + | |style="background:#ABCDEF;" align="center"| '''Product''' || unknown |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || homologous recombination |
| + | |- | ||
| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00540 fin] | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 8 kDa, 5.192 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 8 kDa, 5.192 | ||
| Line 20: | Line 23: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoVC]]'', ''[[mfd]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoVC]]'', ''[[mfd]]'' | ||
|- | |- | ||
| − | |style="background:#FAF8CC;" align="center"|'''[http:// | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU00540 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU00540 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU00540 DNA_with_flanks] |
| − | |||
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yabK_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yabK_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
| + | |- | ||
| + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yabK_60130_60360_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:fin_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00540]] | ||
|- | |- | ||
|} | |} | ||
__TOC__ | __TOC__ | ||
| + | <br/><br/><br/><br/> | ||
| + | <br/><br/><br/><br/> | ||
| + | <br/><br/><br/><br/> | ||
| + | <br/><br/><br/><br/> | ||
| + | <br/><br/><br/><br/> | ||
| + | |||
<br/><br/> | <br/><br/> | ||
| + | |||
| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[DNA repair/ recombination]]}}, | ||
| + | {{SubtiWiki category|[[sigma factors and their control]]}}, | ||
| + | {{SubtiWiki category|[[sporulation proteins]]}} | ||
| + | |||
| + | = This gene is a member of the following [[regulons]] = | ||
| + | |||
=The gene= | =The gene= | ||
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=== Basic information === | === Basic information === | ||
| − | * ''' | + | * '''Locus tag:''' BSU00540 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | + | sporulation defect (50-fold reduction of viable spore count) and arrest after engulfment {{PubMed|21037003}} | |
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00540&redirect=T BSU00540] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
| Line 47: | Line 66: | ||
=== Additional information=== | === Additional information=== | ||
| + | |||
| + | |||
| Line 71: | Line 92: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
| + | ** [[SigF]]-[[Fin]] (probably) {{PubMed|21037003}} | ||
| − | * '''Localization:''' | + | * '''[[Localization]]:''' localizes diffusely within the forespore compartment of sporangia at both early and late stages of sporulation, cytosolic protein {{PubMed|21037003}} |
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00540&redirect=T BSU00540] | ||
* '''Structure:''' | * '''Structure:''' | ||
| − | * ''' | + | * '''UniProt:''' [http://www.uniprot.org/uniprot/P37553 P37553] |
| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU00540] |
* '''E.C. number:''' | * '''E.C. number:''' | ||
| Line 91: | Line 114: | ||
* '''Operon:''' | * '''Operon:''' | ||
| − | * ''' | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yabK_60130_60360_1 fin] {{PubMed|22383849}} |
| − | * '''Regulation:''' | + | * '''Sigma factor:''' [[SigF]] {{PubMed|21037003}}, [[SigG]] {{PubMed|21037003}} |
| + | |||
| + | * '''Regulation:''' expressed in two waves in the forespore (after two hours ([[SigF]]) and three hours ([[SigG]]) after the onset of sporulation) {{PubMed|21037003}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
| Line 118: | Line 143: | ||
=References= | =References= | ||
| − | + | <pubmed> 15317759 11810266 </pubmed> | |
| − | + | '''Additional publications:''' {{PubMed|21037003}} | |
| + | [[Category:Protein-coding genes]] | ||
Latest revision as of 12:46, 2 April 2014
- Description:
| Gene name | subA |
| Synonyms | yabK |
| Essential | no |
| Product | unknown |
| Function | homologous recombination |
| Gene expression levels in SubtiExpress: fin | |
| MW, pI | 8 kDa, 5.192 |
| Gene length, protein length | 228 bp, 76 aa |
| Immediate neighbours | spoVC, mfd |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
DNA repair/ recombination, sigma factors and their control, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00540
Phenotypes of a mutant
sporulation defect (50-fold reduction of viable spore count) and arrest after engulfment PubMed
Database entries
- BsubCyc: BSU00540
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: localizes diffusely within the forespore compartment of sporangia at both early and late stages of sporulation, cytosolic protein PubMed
Database entries
- BsubCyc: BSU00540
- Structure:
- UniProt: P37553
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation: expressed in two waves in the forespore (after two hours (SigF) and three hours (SigG) after the onset of sporulation) PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
