RibR

• Description: cryptic riboflavin kinase, binds leader (RFN) rib operon mRNA, may have a regulatory role, required for the conversion of S-methyl-cysteine to cysteine
  
  

Gene name	ribR
Synonyms	ytnK
Essential	no
Product	cryptic riboflavin kinase
Function	utilization of S-methyl-cysteine, regulation of rib operon expression
Gene expression levels in SubtiExpress: ribR
Metabolic function and regulation of this protein in SubtiPathways: ribR
MW, pI	26 kDa, 9.278
Gene length, protein length	690 bp, 230 aa
Immediate neighbours	sndA, cmoJ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

poorly characterized/ putative enzymes, sulfur metabolism

This gene is a member of the following regulons

CymR regulon, AscR regulon

The gene

Basic information

• Locus tag: BSU29300

Phenotypes of a mutant

• no growth with S-methyl cysteine PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P94465

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: snaA-tcyJ-tcyK-tcyL-tcyM-tcyN-cmoO-cmoI-cmoJ-ribR-sndA-ytnM PubMed

• Expression browser: ribR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed in the presence of cysteine (CymR) PubMed
  • induced in the presence of S-methyl-cysteine (AscR) PubMed

• Regulatory mechanism:
  • CymR: transcription repression PubMed
  • AscR: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: