Difference between revisions of "TruB"
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=== Additional information=== | === Additional information=== | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
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* '''Modification:''' | * '''Modification:''' | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=truB_1736886_1737815_1 truB] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=truB_1736886_1737815_1 truB] {{PubMed|22383849}} | ||
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* '''Regulation:''' | * '''Regulation:''' | ||
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=References= | =References= | ||
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[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 14:21, 30 December 2013
- Description: tRNA pseudouridine 5S synthase
| Gene name | truB |
| Synonyms | ylxN, ymxF |
| Essential | no |
| Product | tRNA pseudouridine 5S synthase |
| Function | tRNA modification |
| Gene expression levels in SubtiExpress: truB | |
| MW, pI | 34 kDa, 6.648 |
| Gene length, protein length | 927 bp, 309 aa |
| Immediate neighbours | rbfA, ribC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU16660
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: tRNA uridine = tRNA pseudouridine (according to Swiss-Prot)
- Protein family: Type 1 subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P32732
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Jenna Friedt, Fern M V Leavens, Evan Mercier, Hans-Joachim Wieden, Ute Kothe
An arginine-aspartate network in the active site of bacterial TruB is critical for catalyzing pseudouridine formation.
Nucleic Acids Res: 2014, 42(6);3857-70
[PubMed:24371284]
[WorldCat.org]
[DOI]
(I p)
