Difference between revisions of "XlyA"
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' contains an amidase_2 domain (like [[BlyA]], [[CwlA]], [[CwlH]], [[XlyB]]) | + | * '''[[Domains]]:''' |
| + | ** contains four N-acetylglucosamine-polymer-binding [[LysM domain]]s {{PubMed|18430080}} | ||
| + | ** contains an amidase_2 domain (like [[BlyA]], [[CwlA]], [[CwlH]], [[XlyB]]) | ||
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=xlyA_1347289_1348182_1 xlyA] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=xlyA_1347289_1348182_1 xlyA] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' | * '''Regulation:''' | ||
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=References= | =References= | ||
| − | + | == Reviews== | |
| + | <pubmed>18430080</pubmed> | ||
| + | == Original publications == | ||
<pubmed>9555893,21816821,7921239,18957862, </pubmed> | <pubmed>9555893,21816821,7921239,18957862, </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 14:48, 27 December 2013
- Description: N-acetylmuramoyl-L-alanine amidase
| Gene name | xlyA |
| Synonyms | |
| Essential | no |
| Product | N-acetylmuramoyl-L-alanine amidase |
| Function | PBSX prophage-mediated lysis |
| Gene expression levels in SubtiExpress: xlyA | |
| MW, pI | 31 kDa, 5.342 |
| Gene length, protein length | 891 bp, 297 aa |
| Immediate neighbours | xhlB, spoIISB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
cell wall degradation/ turnover, PBSX prophage
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU12810
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot)
- Protein family: LysM repeat (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Localization:
- extracellular (no signal peptide) PubMed
Database entries
- UniProt: P39800
- KEGG entry: [2]
- E.C. number: 3.5.1.28
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Girbe Buist, Anton Steen, Jan Kok, Oscar P Kuipers
LysM, a widely distributed protein motif for binding to (peptido)glycans.
Mol Microbiol: 2008, 68(4);838-47
[PubMed:18430080]
[WorldCat.org]
[DOI]
(I p)
Original publications
