LicC

• Description: lichenan-specific phosphotransferase system, EIIC component of the PTS
  
  

Gene name	licC
Synonyms	celB
Essential	no
Product	lichenan-specific phosphotransferase system, EIIC component
Function	lichenan uptake and phosphorylation
Gene expression levels in SubtiExpress: licC
Interactions involving this protein in SubtInteract: LicC
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	48 kDa, 8.584
Gene length, protein length	1356 bp, 452 aa
Immediate neighbours	licA, licB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

phosphotransferase systems, utilization of specific carbon sources, membrane proteins

This gene is a member of the following regulons

CcpA regulon, LicR regulon

The gene

Basic information

• Locus tag: BSU38580

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: PTS permease, lactose permease (Lac) family PubMed

• Paralogous protein(s): YwbA, GmuC

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • LicB-LicC

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure: 3QNQ (EIIC component of diacetylchitobiose specific PTS from Bacillus cereus; 60% identity, 87% similarity) PubMed

• UniProt: P46317

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: licB-licC-licA-licH PubMed

• Expression browser: licC PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • carbon catabolite repression (CcpA) PubMed
  • induction by oligomeric ß-glucosides (LicR)PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed
  • LicR: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed