PstBB

• Description: phosphate ABC transporter (ATP-binding protein)
  
  

Gene name	pstBB
Synonyms	pstB, yqgK, yzmF
Essential	no
Product	phosphate ABC transporter (ATP-binding protein)
Function	high-affinity phosphate uptake
Gene expression levels in SubtiExpress: pstBB
Interactions involving this protein in SubtInteract: PstBB
MW, pI	29 kDa, 7.767
Gene length, protein length	780 bp, 260 aa
Immediate neighbours	yqzC, pstBA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed 500px

Categories containing this gene/protein

ABC transporters, phosphate metabolism

This gene is a member of the following regulons

PhoP regulon

The gene

Basic information

• Locus tag: BSU24950

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + H₂O + phosphate(Out) = ADP + phosphate + phosphate(In) (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • (PstBA-PstBB)-(PstA-PstC)-PstS PubMed

• Localization:

Database entries

• Structure:

• UniProt: P46342

• KEGG entry: [2]

• E.C. number: 3.6.3.27

Expression and regulation

• Operon: pstS-pstC-pstA-pstBA-pstBB PubMed

• Expression browser: pstBB PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • expressed under conditions of phosphate limitation (5000-fold induced) (PhoP) PubMed

• Regulatory mechanism:
  • PhoP: transcription activation PubMed

• Additional information:
  • mRNA processing between pstS and pstC to maintain higher concentrations of PstS relative to other components of the ABC transporter PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Marion Hulett, University of Illinois at Chicago, USA Homepage