RapC

• Description: response regulator aspartate phosphatase, controls ComA activity
  
  

Gene name	rapC
Synonyms	yclL
Essential	no
Product	response regulator aspartate phosphatase
Function	control of ComA activity
Gene expression levels in SubtiExpress: rapC
Interactions involving this protein in SubtInteract: RapC
MW, pI	45 kDa, 5.024
Gene length, protein length	1146 bp, 382 aa
Immediate neighbours	yclK, phrC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

genetic competence, protein modification, transcription factors and their control, quorum sensing

This gene is a member of the following regulons

CodY regulon, ComA regulon

The gene

Basic information

• Locus tag: BSU03770

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: control of ComA activity PubMed

• Protein family: RAP family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: binding of PhrC to RapC prevents it from binding ComA PubMed

• Interactions:
  • RapC-PhrC PubMed, RapC-ComA PubMed

• Localization:

Database entries

• Structure:

• UniProt: P94415

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: rapC-phrC PubMed

• Expression browser: rapC PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • expressed at high cell density (ComA) PubMed

• Regulatory mechanism:
  • ComA: transcription activation (ComA) PubMed
  • CodY: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: