Difference between revisions of "YfkJ"
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| − | * '''Description:''' general stress protein, [[protein kinases and phosphatases|protein tyrosine phosphatase]] <br/><br/> | + | * '''Description:''' general stress protein, [[protein kinases and phosphatases|protein tyrosine phosphatase]], required for protection against paraquat stress <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Product''' || [[protein kinases and phosphatases|protein tyrosine phosphatase]] | |style="background:#ABCDEF;" align="center"| '''Product''' || [[protein kinases and phosphatases|protein tyrosine phosphatase]] | ||
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || survival of | + | |style="background:#ABCDEF;" align="center"|'''Function''' || survival of stress conditions |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07880 yfkJ] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07880 yfkJ] | ||
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
{{SubtiWiki category|[[protein modification]]}}, | {{SubtiWiki category|[[protein modification]]}}, | ||
| − | {{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}} | + | {{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}}, |
| + | {{SubtiWiki category|[[resistance against oxidative and electrophile stress]]}} | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yfkJ_862004_862474_1 yfkJ] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yfkJ_862004_862474_1 yfkJ] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' SigA {{PubMed|11532142}}, [[SigB]] {{PubMed|15805528,11532142}} | + | * '''[[Sigma factor]]:''' SigA {{PubMed|11532142}}, [[SigB]] {{PubMed|15805528,11532142}} |
* '''Regulation:''' induced by stress ([[SigB]]) {{PubMed|15805528,11532142}} | * '''Regulation:''' induced by stress ([[SigB]]) {{PubMed|15805528,11532142}} | ||
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=References= | =References= | ||
| − | <pubmed>15866923,15995210,,15805528,11532142 </pubmed> | + | <pubmed>15866923,15995210,22582280,15805528,11532142 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:20, 15 September 2013
- Description: general stress protein, protein tyrosine phosphatase, required for protection against paraquat stress
| Gene name | yfkJ |
| Synonyms | |
| Essential | no |
| Product | protein tyrosine phosphatase |
| Function | survival of stress conditions |
| Gene expression levels in SubtiExpress: yfkJ | |
| MW, pI | 17 kDa, 4.563 |
| Gene length, protein length | 468 bp, 156 aa |
| Immediate neighbours | yfkK, yfkI |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
protein modification, general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU07880
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate (according to Swiss-Prot)
- Protein family: low molecular weight phosphotyrosine protein phosphatase family (according to Swiss-Prot)
- Paralogous protein(s): YwlE
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 4ETM
- UniProt: O35016
- KEGG entry: [3]
- E.C. number: 3.1.3.48
Additional information
Expression and regulation
- Sigma factor: SigA PubMed, SigB PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Alexander Reder, Dirk Höper, Ulf Gerth, Michael Hecker
Contributions of individual σB-dependent general stress genes to oxidative stress resistance of Bacillus subtilis.
J Bacteriol: 2012, 194(14);3601-10
[PubMed:22582280]
[WorldCat.org]
[DOI]
(I p)
Lucia Musumeci, Cristina Bongiorni, Lutz Tautz, Robert A Edwards, Andrei Osterman, Marta Perego, Tomas Mustelin, Nunzio Bottini
Low-molecular-weight protein tyrosine phosphatases of Bacillus subtilis.
J Bacteriol: 2005, 187(14);4945-56
[PubMed:15995210]
[WorldCat.org]
[DOI]
(P p)
Ivan Mijakovic, Lucia Musumeci, Lutz Tautz, Dina Petranovic, Robert A Edwards, Peter Ruhdal Jensen, Tomas Mustelin, Josef Deutscher, Nunzio Bottini
In vitro characterization of the Bacillus subtilis protein tyrosine phosphatase YwqE.
J Bacteriol: 2005, 187(10);3384-90
[PubMed:15866923]
[WorldCat.org]
[DOI]
(P p)
Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528]
[WorldCat.org]
[DOI]
(P p)
C W Price, P Fawcett, H Cérémonie, N Su, C K Murphy, P Youngman
Genome-wide analysis of the general stress response in Bacillus subtilis.
Mol Microbiol: 2001, 41(4);757-74
[PubMed:11532142]
[WorldCat.org]
[DOI]
(P p)
