opcR

168

transcriptional repressor of the opuBA-opuBB-opuBC-opuBD and opuCA-opuCB-opuCC-opuCD operons

Locus: BSU_33840

Molecular weight: 21.61 kDa

Isoelectric point: 5.84

Protein length: 185 aa

Gene length: 558 bp

Function: regulation of choline uptake

Product: transcription repressor

Essential: no

Synonyms: opcR, yvbF

Genomic Context

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List of homologs in different organisms, belongs to COG1510 (Galperin et al., 2021)

Gene

Coordinates: 3,471,266  3,471,823

The protein

Catalyzed reaction/ biological activity

• transcriptional repression of the ''opuBA-opuBB-opuBC-opuBD and opuCA-opuCB-opuCC-opuCD'' operons PubMed

Protein family

• GbsR family (with GbsR and YvaV, according to UniProt)

Domains

• HTH marR-type domain (aa 28-79) (according to InterPro)

Structure

• O34709 (AlphaFold)

Paralogous protein(s)

• YvaV

Expression and Regulation

Operons

• Genes: opcR

  Description: PubMed

Biological materials

Mutant

• MGNA-A458 (yvbF::erm), available at the NBRP B. subtilis, Japan
• BKE33840 (opcR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACAGCTGATCATCCCTTCA,  downstream forward: _UP4_AAATAAGAGAGCTGCTTTTT
• BKK33840 (opcR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACAGCTGATCATCCCTTCA,  downstream forward: _UP4_AAATAAGAGAGCTGCTTTTT

References

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